Download Approaches to the Conformational Analysis of by Roger L. Lundblad PDF

By Roger L. Lundblad

ISBN-10: 1439807809

ISBN-13: 9781439807804

The job of many biopharmaceutical polymers depends on conformation, and the subsequent numerous years will see elevated curiosity within the conformational research of those polymers as a result of the advance of biosimilar or "follow-on" organic items. whereas a large choice of ways to research exists, discovering the main manageable ones will be a lot more straightforward with a consolidated reference that info the advantages and value of every method, with an emphasis on genuine effects and genuine items. Explores the growing to be function of Conformational research in evaluating well-known Biopharmaceuticals ways to the Conformational research of Biopharmaceuticals gathers the main invaluable ideas and techniques right into a unmarried quantity, placing the best emphasis on these techniques that experience confirmed the main fruitful. instead of conceal particular makes use of of recommendations intimately, this booklet offers advertisement biotechnologists and researchers with the data and references they should make stable offerings concerning the expertise they decide to use. With various references that direct readers to basic resource fabric, it contains reviews drawn from the gamut of present literature, overlaying actual tools, comparable to differential scanning calorimetry, mild scanning, and analytical ultracentrifugation. It additionally addresses chemical tools, resembling hydrogen–deuterium trade and hint labeling, besides infrared, ultraviolet, and Raman spectroscopy. Written through Roger Lundblad, a real pioneer in protein technological know-how, this quantity provides the mandatory info researchers have to entry whilst deciding upon the main reasonable technique, together with: comparison of biopharmaceuticals Characterization of follow-on biologics caliber attributes of protein biopharmaceuticals Confrontational research of biopharmaceutical items With a transparent concentrate on suitable advertisement biotechnology, this e-book belongs at the cabinets of these critical researchers who're paving the way in which for the following new release of biopharmaceutical polymers.

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Extra resources for Approaches to the Conformational Analysis of Biopharmaceuticals (Protein Science)

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Acta 1774, 813–821, 2007. 104. Day, R. , Water penetration in the low and high pressure native states of ubiquitin, Proteins 70, 1175–1184, 2008. 105. , Measuring conformational stability of proteins using an optimized temperature-controlled capillary electrophoresis approach, J. Chromatogr. A 838, 157–165, 1999. 106. , Differences between the pressure- and temperature-induced denaturation and aggregation of beta-lactoglobulin A, B, and AB monitored by FT-IR spectroscopy and small-angle X-ray scattering, Biochemistry 38, 6512–6519, 1999.

W. , Determination of moisture content of lyophilized allergen vaccines by NIR spectroscopy, J. Pharm. Biomed. Anal. 46, 592–596, 2008. 275. , Sparén, A. , Applying spectral peak area analysis in nearinfrared spectroscopy moisture assays, J. Pharm. Biomed. Anal. 44, 127–136, 2007. 276. , Direct determination of moisture in powder milk using near infrared spectroscopy, J. Autom. Methods Manag. Chem. 2, 51342, 2006. 277. , Immunogenicity of proteins administered to humans for therapeutic purposes, Trends Biotechnol.

258. , The structural aspects of limited proteolysis of native proteins, Biochim. Biophys. Acta 1382, 191–206, 1998. 259. , Frigo, M. , Limited proteolysis of bovine α-lactalbumin: Isolation and characterization of protein domains, Protein Sci. 8, 2290–2303, 1999. 260. A. , Study of calcineurin structure by limited proteolysis, Methods Mol. Biol. 172, 317–334, 2002. Introduction to Biopharmaceutical Conformational Analysis 17 261. , Gottardo, R. , Partly folded states of members of the lysozyme/lactalbumin superfamily: A comparative study by circular dichroism spectroscopy and limited proteolysis, Protein Sci.

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Approaches to the Conformational Analysis of Biopharmaceuticals (Protein Science) by Roger L. Lundblad

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